September 23, 2006 - From the Arrowhead Pond in Anaheim, California. UFC Welterweight Champion Matt Hughes defends his title against the man who defeated him at UFC 46 - BJ Penn. Plus, a middleweight showdown that could decide who is next in line for a title fight as The Ultimate Fighter season one's Mike Swick takes on Canadian David "The Crow" Loiseau.
Fighters featured on the undercard include Jens Pulver, Rashad Evans, Melvin Huillard, Jason Lambert, Jorge Gurgel, and Roger Huerta. A total of 9 bouts.
